Variant Prolactin Receptor in Agalactia and Hyperprolactinemia
نویسندگان
چکیده
منابع مشابه
Detection of macroprolactin causing hyperprolactinemia in commercial assays for prolactin.
one at the concentration of 7 pg/mg. This result was not challenged by the athlete. Nandrolone has also been identified by this laboratory in the hair of bodybuilders, in concentrations of 1–7 pg/mg (8 ). NA and noretiocholanolone were not detected in any hair. The sensitive, specific, and reproducible method developed appears to be suitable for the detection and quantification of 19-norsteroid...
متن کاملAssociation of Prolactin and Prolactin Receptor Gene Polymorphisms with Economic Traits in Breeder Hens of Indigenous Chickens of Mazandaran Province
Polymorphisms in 5’-flanking region of prolactin (PRL), exon 2 and exon 5 of prolactin receptor (PRLR) genesand its association with growth and egg traits were examined in breeder hens of Mazandaran native fowlsbreeding station. A single nucleotide polymorphism at site C-2402T and a 24 bp nucleotide sequence insertionat situation -382 in 5’-flanking regions of PRL gene were id...
متن کاملEffects of metoclopramide-induced hyperprolactinemia on the prolactin receptor of murine endometrium.
OBJECTIVE To evaluate the effects of metoclopramide-induced hyperprolactinemia on the prolactin receptor of murine endometrium. DESIGN Experimental study using the RNA extraction to detect tissue prolactin receptor isoforms by reverse-transcriptase polymerase chain reaction (RT-PCR). SETTING University-based laboratory. ANIMAL(S) Seventy-two female swiss albino mice (Mus musculus), approx...
متن کاملLymphocytic prolactin does not contribute to systemic lupus erythematosus hyperprolactinemia.
OBJECTIVES Lymphocytic prolactin (PRL) gene expression is detected in the majority of the immune cells and it is not known if this source contributes to hyperprolactinemia in systemic lupus erythematosus (SLE). We have therefore evaluated lymphocytic PRL secretion and gene expression in SLE and healthy controls. METHODS Thirty SLE patients (ACR criteria) and 10 controls were selected for the ...
متن کاملProlactin Receptor Expression and Prolactin-mediated Effects in Adipose Tissue
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2018
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa1805171